The following are some list of Secondary schools in the Upper west Region:
| Daffiamah Sec | Nadawli | Upper West Region |
| Eremon Sec/Tech | Lawra | Upper West Region |
| Islamic Senior Sec | Wa | Upper West Region |
| Jirapa Snr Sec Day | Jirapa/Lambushie | Upper West Region |
| Kaleo Sec/Tech | Nadawli | Upper West Region |
| Kanton Secondary | Sisala/Tumu | Upper West Region |
| Ko Snr Secondary | Lawra | Upper West Region |
| Lawra Secondary | Lawra | Upper West Region |
| Lessie-Tuolu Senior Sec | Wa | Upper West Region |
| Nandom Sec | Lawra | Upper West Region |
| Nandom Secondary | Lawra | Upper West Region |
| Piina Secondary | Jirapa/Lambushie | Upper West Region |
| Queen of Peace Sec | Nadawli | Upper West Region |
| Queen of Peace Senior High School | Nadawli | Upper West Region |
| St Francis Girls Sec | Jirapa/Lambushie | Upper West Region |
| St Francis Girls Sec | Jirapa/Lambushie | Upper West Region |
| St Francis Xavier Jnr Seminary | Wa | Upper West Region |
| St. Ignatious of Loyola Senior High School | Wa | Upper West Region |
| Tumu Sec/Tech | Sisala/Tumu | Upper West Region |
| Ulo Secondary | Jirapa/Lambushie | Upper West Region |
| Wa Sec/Tech | Wa | Upper West Region |
| Wa Secondary | Wa | Upper West Region |